NAD+ IV Dose Guide: 100mg vs 500mg vs 1000mg

So, you’ve decided to get the miracle molecule, but are confused about the dosage?

You’ve come to the right place.

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You've done the research. Now, let's get you the right dose guide.

You already know that the therapy can sharpen your thinking, restore your energy, and repair your cells. But then you look at the menu.

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100mg. 500mg. 1000mg. Price differences of thousands of dirhams between them. And somehow, nobody gives you a straight answer about which one you actually need.

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That question matters more than you think.

Choose too low, and you'll waste lots of time and feel almost nothing. Choose too high, and you'll spend your session with chest tightness and nausea.

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We see both scenarios. Regularly.

Patients who've wasted AED 6,000 on underdosed sessions at clinics that picked a number and hoped for the best.

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Below, our clinical team at our DHA-licensed Dubai facility breaks down exactly what each dose does, who it's genuinely right for, and how we determine your starting point.

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At a Glance: What the Numbers Actually Mean
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Is It Normal For NAD+ to Decline?

Yes.

By the time you're in your mid-thirties, your NAD+ levels drop significantly. By sixty, you may have less than half of what you had in your twenties.

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If you don’t feel the symptoms of decline, let me help you with some examples. Io you suffer from afternoon energy crashes, slower recovery, and a foggy kind of thinking that used to be sharp, then you’re already experiencing the NAD+ decline.

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NAD+ is a coenzyme found in every cell of your body. It repairs DNA and regulates inflammation. Without enough of it, your cells are running on a depleted battery, and no amount of sleep or coffee fully compensates.

Why Delivery is Important

Oral supplements work in a limited capacity. Since they have to survive digestion, get absorbed, and then be converted into NAD+. A lot gets lost along the way.

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IV delivery skips all of that. NAD+ goes directly into your bloodstream, raising plasma levels within hours.

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But here's what matters: how fast it goes in matters just as much as how much you take. That’s why it’s essential to get an overview of the most common dosage options.

The 100mg Dose: A Gentle Start

If you hear "100mg" and assume it's the budget option, you’re wrong. Some people are of the opinion that this dose is for people who are not serious.

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That's the wrong way to think about it.

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100mg is our starting dose for first-time patients and for those maintaining results after a higher-dose protocol. It’s also taken by people who are smaller in body weight or sensitive to IV therapies. At this level, most patients notice something: better sleep, a subtle lift in mental clarity, and a cheerful mood.

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It's not dramatic. That's the point.

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The patients who respond most noticeably at this dose are usually people who are broadly healthy but running on empty. For example, people with early burnout and disrupted sleep.

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That’s why celebrities like Kendall Jenner, Jennifer Aniston, Gwyneth Paltrow, and Joe Rogan often use IV drips to boost NAD+ levels.

The 500mg Dose: Where Most People Begin

Are you one of those people suffering from fatigue, brain fog, post-viral symptoms, or athletic recovery goals? Or you’re over 40 who's noticed their sharpness isn't quite what it was.

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Don’t worry, we’ve all been there.

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At this level, many patients feel something during the infusion itself. A mental clarity that arrives quietly. Within 48–72 hours, the improvements in energy, mood, and cognitive function typically become more obvious. 

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That’s why 500mg is widely considered as the clinical workhorse in the NAD+ world.

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The research supports it. In adults over 60, 500mg-range infusions have shown improved performance on cognitive measures. In athletes, improved mitochondrial efficiency supports faster muscle recovery.

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At our clinic, most patients start here: 8 sessions over 3–4 weeks, with a clinical review at the midpoint.

The 1000mg Dose: When You Need the Full Force

If you’ve reached this part, you know that “1000mg” is definitely not for beginners. It's a clinically intensive protocol, reserved for specific circumstances.

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This mega dose is most commonly used in addiction recovery, neurological rehabilitation, and post-COVID recovery.

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This is serious territory. We're talking about people recovering from cocaine or alcohol dependence. People navigating traumatic brain injury or early neurodegeneration. People still struggling with persistent fatigue and cognitive fog.

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At 1000mg, the sessions are long (sometimes up to six hours), and the infusion rate must be titrated carefully throughout. This is not a dose you administer and walk away from. It demands proper supervision.

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Done well, it can be genuinely transformative. Done carelessly, it's the scenario that gives IV therapy a bad reputation.

Is This Right for You?

It’s right for you if you are:

• A person experiencing chronic fatigue and brain fog.
• An athlete looking to accelerate recovery and push past a performance plateau.
• An adult over 40 noticing early signs of cognitive or physical decline.
• Someone in post-viral recovery, especially post-COVID.
• A person in addiction recovery seeking support under medical supervision.
• A frequent traveller or expat managing jet lag, disrupted sleep, and relentless schedules.

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You shouldn’t take it if you:

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• Are pregnant or breastfeeding
• Have an active or suspected malignancy
• Have severe low blood pressure
• Have a history of haemolytic anaemia or G6PD deficiency
• Decompensated cardiac or renal failure

What To Expect

Before you arrive, drink at least 500ml of water. Skip the heavy meal in the hour prior. Wear comfortable clothing with easy access to your arm. And give yourself a few minutes to cool down from Dubai's heat before your session begins.

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If you’re feeling nervous, it’s alright.

We’ve all been there

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Once you're settled, the infusion begins. At 500mg and above, some patients notice transient sensations: mild chest tightness, warmth, slight tingling, and occasionally nausea. These aren't dangerous. They're rate-dependent, and they resolve within minutes of a simple adjustment. You will not be left alone during your session.

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Afterward, most patients describe a certain kind of calm. Not sedation, not stimulation, just a gentle settling calm. Many sleep unusually deeply the first night. If you’re someone with insomnia or paranoia, it’s meaningful.

What It Costs

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These figures reflect pharmaceutical-grade NAD+, physician-led protocols, and properly supervised infusions in a DHA-licensed facility.

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What you're paying for, beyond the price of the molecule itself. The cost also involves the judgment of a qualified physician, and that is not a trivial thing when something is going directly into your bloodstream.

A Note on Safety and Regulation in the UAE

In Dubai, IV therapies fall under the regulatory authority of the Dubai Health Authority. Any legitimate clinic must hold a current DHA facility licence. The prescribing physician must hold a valid DHA or MOHAP licence. 

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And treatment must follow a medical consultation from a website. Our clinic meets all of these requirements. All NAD+ used in our protocols is pharmaceutical grade, sourced through regulated supply chains, and handled in accordance with UAE sterile compounding standards.

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Ask any clinic you consider the same questions. If they can't answer clearly, that's an answer in itself.

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